Cialis 5mg (Tadalafil) blocks the action of the enzyme PDE-5, which destroys cyclic guanosine monophosphate (cGMP). As a result, the smooth muscles of the penis relax and blood flow increases in it, which leads to an erection.
Scientific research on tadalafil has been conducted in various countries around the world. They have shown that the drug is an effective and safe treatment for erectile dysfunction.
One study conducted in the United States involved more than 2,000 men with erectile dysfunction. They took tadalafil for 12 weeks. The results of the study showed that the drug significantly improved erectile function in most participants.
Another study conducted in Europe involved more than 1,000 men with erectile dysfunction. They also took tadalafil for 12 weeks. The results of the study were similar: the drug significantly improved erectile function in most participants.
Side effects
Like any other drug, tadalafil (cialis) can cause side effects. The most common side effects are headache, dyspepsia (indigestion), nasal congestion and flushes of blood to the face.
Contraindications
Tadalafil is contraindicated in the following conditions:
- hypersensitivity to tadalafil or any other component of the drug;
- simultaneous administration of drugs containing nitrates;
- severe heart failure;
- unstable angina pectoris;
- uncontrolled arterial hypertension;
- stroke or myocardial infarction suffered during the last 6 months.
Tadalafil is an effective and safe treatment for erectile dysfunction. However, before taking the drug, it is necessary to consult a doctor.
Sources:
- Instructions for the medical use of the drug Cialis (tadalafil).
- Montorsi P., et al.
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